Statins such as atorvastatin, lovastatin, and simvastatin.The antihistamine astemizole, fexofenadineĪdditional drugs found to be affected by grapefruit juice include, but are not limited to:.Benzodiazepines, including: alprazolam (Xanax), diazepam (Valium), midazolam (Versed), lorazepam (Ativan), oxazepam, and chlordiazepoxide (Librium).Valproate semisodium, divalproex sodium, Depakote, Epival.Bupropion, amfebutamone, Wellbutrin.The following drugs interact with CYP3A4: However, bioactive compounds in grapefuit juice may also interfere with p-glycoprotein and organic anion transporting polypeptides (OATPs) either increasing or decreasing bioavailability of a number of drugs. This is due to the fruit's relatively high concentration of naringin, bergamottin, and dihydroxybergamottin, which interfere with the intestinal enzyme cytochrome P450 isoform CYP3A4. Grapefruit and grapefruit juice has the potential to interaction with numerous drugs. List of terms related to List of drugs affected by grapefruitĮditor-In-Chief: C. Patents on List of drugs affected by grapefruit List of drugs affected by grapefruit in the Marketplace List of drugs affected by grapefruit en Francais List of drugs affected by grapefruit en Espanol Treatment of List of drugs affected by grapefruitĬME Programs on List of drugs affected by grapefruit Symptoms of List of drugs affected by grapefruitĬauses & Risk Factors for List of drugs affected by grapefruitĭiagnostic studies for List of drugs affected by grapefruit Risk calculators and risk factors for List of drugs affected by grapefruit Patient Handouts on List of drugs affected by grapefruitĭirections to Hospitals Treating List of drugs affected by grapefruit Patient resources on List of drugs affected by grapefruitĭiscussion groups on List of drugs affected by grapefruit News trends on List of drugs affected by grapefruitīlogs on List of drugs affected by grapefruitĭefinitions of List of drugs affected by grapefruit List of drugs affected by grapefruit in the newsīe alerted to news on List of drugs affected by grapefruit NICE Guidance on List of drugs affected by grapefruitįDA on List of drugs affected by grapefruitĬDC on List of drugs affected by grapefruitīooks on List of drugs affected by grapefruit US National Guidelines Clearinghouse on List of drugs affected by grapefruit
#GRAPEFRUIT JUICE INTERACTIONS TRIAL#
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